Welcome to the JP lab.
Cell division is a fundamental molecular process of life that ensures accurate transfer of genetic information through generations. Errors in cell division often result in daughter cells with inappropriate numbers of chromosomes, a condition associated with cancers and Down’s syndrome. Hence, understanding the molecular mechanisms of cell division is crucial in fighting cancer.
We study the molecular mechanisms of accurate cell division by structurally and biochemically characterizing key regulators (multi-subunit protein complexes) of cell division.