Publications

2017

1. Spiller F*, Medina-Pritchard M*, Abad MA*, Wear MA, Molina O, Earnshaw WC and Jeyaprakash AA. Molecular Basis for Cdk1 Regulated Timing of Mis18 Complex Assembly and CENP-A Deposition. EMBO Rep. Apr 4. doi: 10.15252/embr.201643564 (*equal contribution)

Pubmed

2016

2. Molina O, Vargiu G, Abad MA, Zhiteneva A, Jeyaprakash AA, Masumoto H, Kouprina N, Larionov V and Earnshaw WC. Epigenetic Engineering Reveals  a Balance Between Histone Modifications and Transcription in Kinetochore Maintenance. Nat Commun. Nov 14;7:13334. doi: 10.1038/ncomms13334.

Pubmed

3. Capalbo L, Mela I, Abad MA, Jeyaprakash AA, Edwardson JM and D’Avino PP. The ESCRT-III Component CHMP4C is Regulated Via a Relay Mechanism During Abscission. Open Biol. Oct;6(10).pii: 160248. doi: 10.1098/rsob.160248. 

Pubmed

4. Abad MA, Zou J, Medina-Pritchard M, Nigg EA, Rappsilber J, Santamaria A and Jeyaprakash AA. (2016) Ska3 Ensures Timely Mitotic Progression by Interacting Directly with Microtubules and Ska1 Microtubule Binding Domain. Sci Rep. 6, 34042; doi: 10.1038/srep34042.

Pubmed

5. Subramanian L*, Medina-Pritchard B*, Barton R, Spiller F, Kulasegaran-Shylini R, Radaviciute G, Allshire RC and Jeyaprakash AA. (2016) Centromere Localisation and Function of Mis18 Requires Yipee-Like Domain-Mediated Oligomerisation. EMBO Rep. Apr;17(4):496-507. doi: 10.15252/embr.201541520. Epub 2016 Feb 26. (*equal contribution)

Pubmed

2015

6. Papini D, Langemeyer L, Abad MA, Kerr A, Samejima I, Eyers PA, Jeyaprakash AA, Higgins JMG, Barr FA and Earnshaw WC. (2015) TD60 Links RalA GTPase Function to the CPC in Mitosis. Nat Commun. Jul 9;6:7678. doi:10.1038/ncomms8678

Pubmed

7. Platani M, Trinkle-Mulchay L, Porter M, Jeyaprakash AA and Earnshaw WC. (2015) Mio Depletion Links mTOR Regulation to Aurora A and Plk1 Activation at Mitotic Centrosomes. J Cell Biol. Jun 28.  pii: jcb.201410001. [Epub ahead of print]

Pubmed

2014

8. Abad MA*, Medina B*, Santamaria A*, Zou J, Plasberg-Hill C, Madhumalar A, Jayachandran U, Redli PM, Rappsilber J, Nigg EA and Jeyaprakash AA. (2014) Structural Basis for Microtubule Recognition by the Human Kinetochore Ska complex. Nat Commun. Jan 13;5:2964. doi: 10.1038/ncomms3964. (*equal contribution)

Pubmed

2013

9. Sharma A, Pohlentz G, Bobbili KB, Jeyaprakash AA, Chandran T, Mormann M, Swamy MJ and Vijayan M. (2013) The Sequence and Structure of Snake Gourd (Trichosanthes Anguina) Seed Lectin, a Three-Chain Nontoxic Homologue of Type II RIP Acta Cryst. August; D69, 1493-1503. Epub 2013 Jul 18.

Pubmed

2012

10. Jeyaprakash AA, Santamaria A, Jayachandran U, Chan YW, Benda C, Nigg EA and Conti E. (2012) Structural and Functional Organization of the Ska Complex, a Key Component of the Kinetochore-Microtubule Interface. Mol Cell. May 11;46(3):274-286. Epub 2012 Apr 5.

Pubmed

11. Chan YW, Jeyaprakash AA, Nigg EA and Santamaria A. (2012) Aurora B Controls Kinetochore-Microtubule Attachments by Inhibiting Ska Complex-KMN Network Interaction. J Cell Biol. Mar 5;196(5):563-71. Epub 2012 Feb 27.

Pubmed

2011

12. Jeyaprakash AA§, Basquin C, Jayachandran U, Conti E§. (2011) Structural Basis for the Recognition of Phosphorylated Histone H3 by the Survivin Subunit of the Chromosomal Passenger Complex. Structure. Nov 09;19(11):1625-34. Epub 2011 Oct 25 (§Corresponding Authors)
Pubmed

2009

13. Gaitanos TN, Santamaria A, Jeyaprakash AA, Wang B, Conti E, Nigg EA. (2009) Stable Kinetochore-Microtubule Interactions Depend on the Ska Complex and its New Component Ska3/C13orf3. EMBO J. May 20;28(10):1442-52. Epub 2009 Apr 9. Pubmed

2007

14. Jeyaprakash AA*, Klein UR*, Lindner D, Ebert J, Nigg EA, Conti E. (2007) Structure of a Survivin-Borealin-INCENP Core Complex Reveals How Chromosomal Passengers Travel Together. Cell. Oct 19;131(2):271-85. (*equal contribution)
Pubmed 
(Comments in:
1. Ruchaud S, Carmena M, and Earnshaw WC. The Chromosomal Passenger Complex: One for all and all for one. Cell (2007) 131, 230-231.
2. Heinrichs A. Cell Cycle Passengers travel together. Nat. Rev. Mol. Cell. Biol (2007) 8, 944.)

MPI Press Release

2005

15. Jeyaprakash AA, Jayashree G, Mahanta SK, Swaminathan CP, Sekar K, Surolia A, Vijayan M. (2005) Structural Basis for the Energetics of Jacalin-Sugar Interactions: Promiscuity Versus Specificity. J Mol Biol. Mar 18;347(1):181-8. Epub 2005 Jan 18.
Pubmed

2004

16. Jeyaprakash AA, Srivastav A, Surolia A, Vijayan M. (2004) Structural Basis for the Carbohydrate Specificites of Artocarpin: Variation in the Length of a Loop as a Strategy for Generating Ligand Specificity. J Mol Biol. May 7;338(4):757-70.
Pubmed

17. Natchiar SK, Jeyaprakash AA, Ramya TNC, Thomas CJ, Suguna K, Surolia A, Vijayan M. (2004) Structural Plasticity of Peanut Lectin: An X-ray Analysis Involving Variation in pH, Ligand Binding and Crystal Structure. Acta Crystallogr D Biol Crystallogr Feb;60(Pt2):211-9. Epub 2005 Jan 23.
Pubmed

2003

18. Sekar K, Mala SV, Rajakannan V, Yogavel M, Velmurugan D, Poi MJ, Vishwanath S, Gowda TV, Jeyaprakash AA, Tsai MD. (2003) Crystal Structure of the Free and Anisic Acid Bound Triple Mutant of Phospholipase A2.
J Mol Biol Oct 17;333(2):367-76.

Pubmed

19. Jeyaprakash AA, Katiyar S, Swaminathan CP, Sekar K, Surolia A, Vijayan M. (2003) Structural Basis of the Carbohydrate Specificities of Jacalin: An X-ray and Modeling Study. J Mol Biol Sep 5;332(1):217-28.
Pubmed

2002

20. Rajakannan V, Yogavel M, Poi MJ, Jeyaprakash AA, Jeyakanthan J, Velmurugan D, Tsai MD, Sekar K. (2002) Observation of Additional Calcium Ion in the Crystal Structure of the Triple Mutant K56,120,121M of Bovine Pancreatic Phospholipase A2. J Mol Biol Dec 6;324(4):755-62.
Pubmed

21. Jeyaprakash AA, Rani PG, Reddy GB, Banumathi S, Betzel C, Sekar K, Surolia A, Vijayan M. (2002) Crystal Structure of the Jacalin-T-antigen Complex and a Comparative Study of Lectin-T-antigen Complexes. J Mol Biol Aug 23;321(4):637-45.
Pubmed

22. Pratap JV, Jeyaprakash AA, Rani PG, Sekar K, Surolia A, Vijayan M. (2002) Crystal Structures of Artocarpin, a Moraceae Lectin with Mannose Specificity, and its Complex with Methyl-alpha-D-Mannose: Implications to the Generation of Carbohydrate Specificity. J Mol Biol Mar 22;317(2):237-47.
Pubmed

2001

23. Adhikari P, Bachhawat-Sikder K, Thomas CJ, Ravishankar R, Jeyaprakash AA, Sharma V, Vijayan M, Surolia A. (2001) Mutational Analysis at Asn41 in Peanut Agglutinin. A Residue Critical for the Binding of the Tumor-Associated Thomsen-Friedenreich Antigen. J Biol Chem Nov 2;276(44):40734-9. Epub 2001 Jul 10.
Pubmed

24. Manoj N, Jeyaprakash AA, Pratap JV, Komath SS, Kenoth R, Swamy KJ, Vijayan M. (2001) Crystallization and Preliminary X-ray Studies of Snake Gourd Lectin: Homology with TypeII Ribosome-Inactivating Proteins. Acta Crystallogr D Biol Crystallogr Jun;57(pt 6):912-4.
Pubmed